Material may be irritating to the mucous membranes and upper respiratory tract. January 2008 if you would like any more information, or would like the leaflet in a different format, please contact medical information at the above. Lidocaine hydrochloride oral topical solution, usp 2%. May 31, 2017 this is a prospective, randomized, single blinded, twoarm, head to head study. For product protection, follow storage recommendations noted on the product case label, the primary. Downloads product information msds download the msds sheets for our tattoo products and anesthetics from the links below.
When used as a spray, or when applied by means of cotton applicators or packs, as when instilled into a cavity, the suggested dosage of lidocaine hydrochloride topical solution is 15 ml 40200 mg of lidocaine hydrochloride, i. Possible target organs include the nervous system and cardiovascular. Lidocaine hydrochloride injection, usp intravenous for cardiac arrhythmias, is a sterile, nonpyrogenic solution prepared from lidocaine with the aid of hydrochloric acid in water for injection. Lidocaine hydrochloride and epinephrine injection msds. Lidocaine hydrochloride june 28, 2017 page 1of 5 safety data sheet.
Lidocaine hydrochloride monohydrate c14h25cln2o2 pubchem. Your new online msds binder is a place for you to store the material safety data sheets you need to deploy. Identification of the substancemixture and the companyundertaking product identifier material name. Oeb 2 control exposure to the range of 100ugm3 to lidocaine. Lidocaine investigated as a drug, mutagen, primary irritant, and reproductive effector. In the workplace, this material should be considered possibly irritating to the skin, eyes and respiratory tract, and a. Handling and storage precautions for safe handling. Dailymed lidocaine lidocaine hydrochloride injection. Emergency overview metoclopramide metoclopramide hydrochloride injection is a solution containing metoclopramide hydrochloride, a selective dopamine antagonist that increases gut motility. Usp reference standards are rigorously tested and evaluated by multiple independent commercial, regulatory, and academic laboratories to confirm accuracy and reproducibility. Your new online msds binder is a place for you to store the material safety data.
Lidocaine also known as xylocaine or lignocaine is white ctystalline powder. Identification of the substancemixture and of the companyundertaking product name. Occupational and environmental safety office duke university medical. We ask that users who download significant portions of the database cite the hmdb paper in any. The safety and efficacy of 5% lidocaine patch and flurbiprofen patch for relieving acute low back pain. Chemical product and company identification manufacturer name and address lake forest, illinois 60045 hospira, inc. Nevertheless, lidocaines local anesthetic action sees its use in many medical situations. To download or print the safety data sheet for oraqix lidocaine and prilocaine periodontal gel 2. May be harmful by inhalation, ingestion, or skin absorption. Lidocaine hydrochloride was not shown to be mutagenic in the salmonellamammalian microsome test nor clastogenic in chromosome aberration assay with human lymphocytes and mouse micronucleus test. The release liner is removed prior to application to the skin.
It stimulates the motility of the upper gastrointestinal tract without affecting gastric, biliary, or. Information on this msds sheet was obtained from sources which we believe are reliable, and we believe. Department of pharmacy duke university medical center box 3089 durham, nc 27710 9196845125 information department. Material safety data sheet hochunk nation department.
Identification of the substancemixture and of the companyundertaking. Based on available data, the classification criteria are not met. The elimination halflife of lidocaine hcl following an intravenous bolus injection is typically 1. Since it is a local anesthetic, contact with the eyes or skin may cause temporary. Chemical product and company identification manufacturer name and. Our fastacting topical anesthetics for client pain control are specifically formulated with nonprescription strength ingredients and are specifically for permanent cosmetics and other skin sensitive procedures. Lidocaine hydrochloride and epinephrine injection 1. To download right click on the link below and choose save target as to. Dec 31, 2019 lidocaine hydrochloride, chemical name. Msds marcaine bupivacaine hydrochloride injection 101711. Efficacy will be determined by the level of pain relief as measured by. Emergency overview marcaine bupivacaine hydrochloride injection is a solution containing bupivacaine hydrochloride, a local anesthetic used for pain management.
Product identification product name lidocaine, usp product code 0081 supplier medisca inc. If a person vomits place them in the recovery position so that vomit will not reenter the mouth and throat. Approximately 90% of lidocaine hcl administered is excreted in the form of various metabolites, and less than 10% is excreted unchanged. Lidocaine hydrochloride injection, usp, 1% or 2%, contains lidocaine hydrochloride, an amidetype local anesthetic used as a local anesthetic for pain management. Lidocaine hydrochloride and epinephrine injection, solution hospira, inc.
This prevents the generation and conduction of nerve impulses and produces a. The intravenous ld50 of lidocaine hcl in female mice is 26 21 mgkg and the subcutaneous ld50 is 264 203304 mgkg. Compound type route species dosage lidocaine hcl ld50 oral rat 317 mgkg lidocaine hcl ld50 subcutaneous mouse 285 mgkg lidocaine hcl ld50 oral mouse 2 20, 292 mgkg lidocaine hcl ld50 subcutaneous rat 570 mgkg. Lidocaine hydrochloride is the hydrochloride salt from of lidocaine, an aminoethylamide and a prototypical member of the amide class anesthetics. In the workplace, this product should be considered possibly irritating to the skin, eyes and respiratory tract.
Purchase topical anesthetics for permanent makeup procedures. Lidocaine hydrochloride and epinephrine injection page 6 of 6 section 15. Storage no special storage required for hazard control. It is not a specification sheet and none of the displayed data should be construed as a specification. Page 17 safety data sheet according to 19072006ec, article 31 printing date 22. To download right click on the link below and choose save target as to your hard drive. What lidocaine hydrochloride looks like and contents of pack lidocaine hydrochloride is a clear colourless, sterile solution for injection. Lidocaine hydrochloride 7586 not listed not listed not listed epinephrine listed as a hazardous product in the rcra epa and cerla epa regulations. Safety data sheet product name lidocaine hydrochloride. And address 275 north field drive lake forest, illinois 60045. Identification of the substancemixture and of the companyundertaking product identifier xylocaine solution for oral pump spray details of the supplier of the safety data sheet. Copying andor downloading of this information for the purpose of properly utilizing.
Identification of the substancemixture and of the companyundertaking product identifier emla cream details of the supplier of the safety data sheet. Handle in accordance with product label andor product insert information. We offer publicly available, official documentary standards for pharmaceutical ingredients in the usp nf that link directly with a primary reference standard. This compund is known to block voltagegated sodium channels in the inactivated state. Lidocaine hydrochloride 2% solution msdsno 775 tuesday, july 20, 2010 to the best of our knowledge the information contained herein is accurate as of the date hereof. The primary metabolite in urine is a conjugate of 4hydroxy2,6dimethylaniline.
Lidocaine is a selective inverse peripheral histamine h1receptor agonist with an ic 50 of 32. Lidoderm lidocaine patch 5% is comprised of an adhesive material containing 5% lidocaine, which is applied to a nonwoven polyester felt backing and covered with a polyethylene terephthalate pet film release liner. In clinical use, this material is indicated for local or regional anesthesia or analgesia for surgery, dental and oral surgery. This document is generated to distribute health, safety and environmental data. Carbocaine mepivacaine hydrochloride injection solution 3 7. Lidocaine hydrochloride 7586 not listed not listed not listed epinephrine listed as a hazardous product in the rcra epa and. Determining the effect of the 5% lidocaine patch and flurbiprofen patch for improving functional disabilities and in reducing pain resulting from acute low back pain. Safety data sheet product name lidocaine hydrochloride and. Lidocaine is also an anasthetic and class ib antiarrhythmic agent. Material safety data sheet according to iso 110141.
If eye irritation persists, get medical adviceattention. Hospira, formerly the hospital products division of abbott laboratories, was. And address 275 north field drive lake forest, illinois 60045 usa note. Chemical product and company information manufacturer name hospira, inc. Dailymed lidocaine lidocaine hydrochloride injection, solution. Oraqix lidocaine and prilocaine periodontal gel, 2.
Enter synonyms, trade names or additional information found in section 1. Lidocaine hydrochloride oral topical solution, usp 2% viscous 4 of 7 7. Studies in animals have not shown that lidocaine causes adverse effects on the fetus. Lidocaine stabilizes the neuronal membrane by binding to and inhibiting voltagegated sodium channels, thereby inhibiting the ionic fluxes required for the initiation and conduction of. Commonly used as a local anaesthetic in dentistry and for minor surgery. Endurance rx male desensitizer, spray, 10 mg100ml, topical, md science lab, llc, 20150609, 20171001, us us. Sigmaaldrich offers a number of lidocaine products.
Lidocaine is a synthetic aminoethylamide with local anesthetic and antiarrhythmic properties. Immediately call a poison center or medical professional. Safety data sheet safety data sheet in compliance with regulation ec 19072006, regulation ec 12722008 and regulation ec 4532010 1. Safety data sheet in compliance with regulation ec 19072006, regulation ec 12722008 and regulation. Oct 28, 2019 when used as a spray, or when applied by means of cotton applicators or packs, as when instilled into a cavity, the suggested dosage of lidocaine hydrochloride topical solution is 15 ml 40200 mg of lidocaine hydrochloride, i. Metabolites of lidocaine have been shown to be carcinogenic in laboratory animals. Its iupac proper chemical name is 2diethylaminon2,6dimethylphenyl acetamide. Handling and storage handling no special handling required under conditions of normal product use. Edqm, lidocaine hydrochloride msds revision 07, issued date.
If data for a hazard are not included in this document there is no known information at this time. Lidocaine hydrochloride and epinephrine injection is a solution containing lidocaine hydrochloride, an amidetype local anesthetic used as a local anesthetic for pain management, and epinephrine, a vasoconstrictor agent. Regulatory information this product has been classified in accordance with the hazard criteria of the controlled products regulations and the msds contains all the information required by the controlled products regulations. Pfizer inc believes that the information contained in this material safety data sheet is accurate, and while it is provided in good faith, it is without warranty of any kind, expressed or implied. Lidocaine and prilocaine belong to the amide class of local anesthetics. Dosage and administration when lidocaine hydrochloride topical solution 4% is used concomitantly with other products containing lidocaine, the total dose contributed by all formulations must be kept in mind. Out of scope information includes radiopharmaceuticals, contrast media, herbals, homeopathics, and food. Page 1 of 1 msds material safety data sheet product name. Handle in accordance with good industrial hygiene and safety practices. If swallowed, seek medical advice immediately and show the container or label. Official label printer friendly view all sections close all sections. Or lidocaine hcl 2% gel is being prescribed for any of the following. To evaluate and compare the efficacy of 5% lidocaine patch and flurbiprofen patch for treatment of acute low back pain.
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